ꯁꯥꯏꯖ ꯲ ꯑꯩꯆ.ꯄꯤ.ꯑꯦꯝ.ꯁꯤ

ꯁꯥꯏꯖ ꯲ HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯑꯁꯦꯡꯕꯥ ꯃꯍꯧꯁꯥꯒꯤ ꯄꯥꯝꯕꯤꯗꯒꯤ ꯁꯦꯝꯕꯅꯤ, ꯁꯦꯂꯐꯝ ꯍꯦꯟꯅꯥ ꯁꯥꯡꯕꯥ ꯑꯃꯁꯨꯡ ꯍꯦꯟꯅꯥ ꯇꯪꯗꯨ ꯂꯩꯇꯥꯕꯥ ꯌꯥꯕꯥ, ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯐꯖꯅꯥ ꯁꯣꯀꯍꯟꯗꯦ꯫ ꯍꯥꯌꯔꯤꯕꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯇꯣꯉꯥꯟ-ꯇꯣꯉꯥꯅꯕꯥ ꯙꯔꯝꯃꯒꯤ ꯊꯥꯖꯕꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯀꯂꯆꯔꯁꯤꯡꯗꯒꯤ ꯂꯥꯀꯄꯥ ꯅꯠꯠꯔꯒꯥ ꯑꯦꯂꯥꯔꯖꯤ-ꯄ꯭ꯔꯣꯅꯦꯟ ꯂꯩꯕꯥ ꯃꯤꯑꯣꯏꯁꯤꯡꯒꯤ ꯃꯊꯧ ꯇꯥꯕꯁꯤꯡ ꯑꯗꯨ ꯐꯪꯍꯜꯂꯤ꯫

HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯃꯔꯨꯑꯣꯏꯅꯥ ꯍꯥꯏꯒ꯭ꯔꯣꯁ꯭ꯀꯣꯄꯤꯛ, ꯑꯦꯁꯤꯗ-ꯁꯦꯟꯁꯤꯇꯤꯕ, ꯅꯠꯠꯔꯒꯥ ꯏꯔꯤꯇꯦꯟꯇ ꯗ꯭ꯔꯒꯁꯤꯡ ꯑꯦꯅꯀꯦꯄꯁꯨꯂꯦꯠ ꯇꯧꯕꯗꯥ ꯁꯤꯖꯤꯟꯅꯩ, ꯃꯁꯤꯅꯥ ꯃꯩꯁꯥ ꯅꯦꯝꯕꯥ (꯳-꯵%)ꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯊꯦꯡꯊꯕꯥ ꯏꯟꯇꯦꯁ꯭ꯇꯤꯅꯦꯜ ꯔꯤꯂꯤꯖ ꯄꯤ꯫

▶ꯃꯍꯧꯁꯥꯒꯤ ꯄꯥꯝꯕꯤꯒꯤ ꯔꯤꯁꯣꯔꯁ, ꯁꯥꯐꯕꯥ ꯑꯃꯁꯨꯡ ꯇꯪꯗꯨ ꯂꯩꯇꯥꯕꯥ ꯄꯣꯠꯁꯀꯁꯤꯡ꯫

ꯀꯣꯔꯅꯥꯀꯀꯦꯄꯁꯀꯤ ꯎꯍꯩ ꯀꯦꯄꯁꯨꯂꯁꯤꯡꯒꯤ ꯔꯣ ꯃꯦꯇꯔꯤꯌꯦꯜ ꯑꯁꯤ ꯃꯁꯤꯒꯤ ꯍꯣꯜꯗꯤꯡ ꯀꯝꯄꯦꯅꯤꯅꯥ ꯁꯦꯃꯒꯠꯄꯥ ꯑꯃꯁꯨꯡ ꯔꯤꯁꯔꯆ ꯇꯧꯕꯥ HPMCꯅꯤ, ꯃꯁꯤ ꯃꯥꯂꯦꯃꯒꯤ ꯗ꯭ꯔꯒ ꯁꯦꯐꯇꯤ ꯑꯣꯊꯣꯔꯤꯇꯤꯁꯤꯡꯅꯥ ꯑꯌꯥꯕꯥ ꯄꯤꯕꯥ ꯃꯍꯧꯁꯥꯒꯤ ꯄ꯭ꯂꯥꯟꯇꯦꯠ ꯁꯦꯂꯨꯂꯣꯖ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯃꯈꯜ ꯑꯃꯅꯤ ꯑꯃꯁꯨꯡ ꯅꯟ--ꯑꯦꯅꯤꯃꯦꯜ ꯁꯣꯔꯁ, ꯅꯟ-ꯇꯣꯛꯁꯤꯛ, ꯚꯦꯖꯦꯇꯦꯔꯤꯌꯅꯁꯤꯡꯅꯥ ꯌꯥꯝꯅꯥ ꯄꯥꯝꯅꯕꯥ ꯑꯃꯅꯤ꯫

 

▶ꯑꯦꯅꯥꯐꯤꯂꯦꯛꯁꯤꯁ ꯂꯩꯇꯕꯥ꯫

ꯀꯣꯔꯅꯥꯀꯀꯦꯄꯁ HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯃꯍꯧꯁꯥꯒꯤ ꯑꯣꯏꯕꯥ ꯄꯣꯠꯁꯀꯁꯤꯡꯗꯒꯤ ꯁꯦꯝꯕꯅꯤ, ꯑꯦꯅꯥꯐꯤꯂꯦꯛꯁꯤꯁ ꯌꯥꯎꯗꯅꯥ, ꯑꯦꯂꯥꯔꯖꯤ ꯀꯟꯁꯇꯤꯠꯌꯨꯁꯅꯒꯤ ꯀꯥꯡꯂꯨꯞ ꯑꯃꯗꯥ ꯃꯇꯝ ꯁꯥꯡꯅꯥ ꯁꯤꯖꯤꯟꯅꯕꯗꯥ ꯆꯨꯅꯕꯥ꯫

 

▶ꯃꯩꯁꯥ ꯁꯦꯟꯁꯤꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯗ꯭ꯔꯒꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯌꯥꯝꯅꯥ ꯐꯕꯥ ꯆꯌꯦꯠꯅꯕꯥ꯫

ꯀꯣꯔꯅꯥꯀꯀꯦꯄꯁ HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯐ꯭ꯔꯤꯖ-ꯁꯨꯡꯕꯥ ꯄꯥꯎꯗꯔ, ꯍꯔꯕꯦꯜ ꯄꯥꯎꯗꯔ, ꯑꯁꯤꯅꯆꯤꯡꯕꯥ ꯃꯩꯁꯥꯗꯥ ꯁꯦꯟꯁꯤꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯄꯣꯠꯊꯣꯀꯁꯤꯡꯅꯥ ꯊꯨꯄꯆꯤꯅꯕꯗꯥ ꯌꯥꯝꯅꯥ ꯆꯨꯝꯃꯤ꯫ ꯃꯁꯤꯅꯥ ꯐꯤꯂꯔꯁꯤꯡꯅꯥ ꯁꯣꯀꯍꯜꯂꯕꯥ ꯀꯦꯄꯁꯨꯂꯁꯤꯡꯗꯥ ꯂꯩꯕꯥ ꯃꯩꯁꯥ ꯑꯗꯨ ꯏꯐꯦꯛꯇꯤꯚ ꯑꯣꯏꯅꯥ ꯊꯤꯡꯕꯥ ꯉꯝꯃꯤ ꯃꯗꯨꯅꯥ ꯁꯣꯀꯍꯅꯕꯗꯥ ꯀ꯭ꯔꯤꯁ꯭ꯄꯀꯤ ꯄ꯭ꯔꯣꯕ꯭ꯂꯦꯝ ꯑꯗꯨ ꯂꯨꯆꯤꯡꯏ꯫ ꯃꯔꯝ ꯑꯗꯨꯅꯥ ꯃꯁꯤ ꯃꯩꯁꯥ-ꯁꯦꯟꯁꯤꯇꯤꯚ ꯐꯤꯂꯔꯁꯤꯡ ꯉꯥꯀꯊꯣꯛꯅꯕꯒꯤꯗꯃꯛ ꯌꯥꯝꯅꯥ ꯐꯕꯥ ꯆꯌꯦꯠꯅꯕꯥ ꯑꯃꯅꯤ꯫

 

▶ꯑꯦꯞꯂꯤꯀꯦꯁꯅꯁꯤꯡꯒꯤ ꯄꯥꯛ ꯆꯥꯎꯔꯕꯥ ꯔꯦꯟꯖ, ꯐꯤꯜꯂꯤꯡ ꯃꯦꯁꯤꯅꯒꯤ ꯃꯊꯧ ꯇꯥꯕꯥ ꯑꯗꯨ ꯐꯪꯍꯅꯕꯥ꯫

ꯀꯣꯔꯅꯥꯀꯀꯦꯄꯁ ꯀꯦꯄꯁꯨꯂꯁꯤꯡꯗꯥ ꯑꯐꯕꯥ ꯏꯂꯥꯁ꯭ꯇꯤꯁꯤꯇꯤ, ꯕ꯭ꯔꯦꯀꯦꯖ-ꯄ꯭ꯔꯨꯐ, ꯑꯋꯥꯡꯕꯥ ꯁ꯭ꯇꯦꯕꯤꯂꯤꯇꯤꯒꯤ ꯀꯥꯟꯅꯕꯥ ꯂꯩ꯫ ꯃꯁꯤꯅꯥ ꯍꯥꯏ-ꯁ꯭ꯄꯤꯗ ꯄꯦꯀꯤꯡ ꯃꯦꯁꯤꯟ ꯑꯃꯗꯥ ꯃꯄꯨꯡ ꯐꯥꯅꯥ ꯄꯥꯡꯊꯣꯀꯄꯥ ꯉꯝꯃꯤ꯫ ꯀꯣꯔꯅꯥꯀꯀꯦꯄꯁ ꯀꯦꯄꯁꯨꯂꯁꯤꯡꯒꯤ ꯃꯑꯣꯡ ꯑꯃꯁꯨꯡ ꯁꯥꯏꯖ ꯑꯁꯤ ꯖꯦꯂꯇꯤꯟ ꯀꯦꯄꯁꯨꯂꯁꯤꯡꯒꯥ ꯃꯥꯟꯅꯩ꯫ ꯑꯦꯞꯂꯤꯀꯦꯁꯅꯗꯥ ꯄꯦꯀꯦꯖꯤꯡ ꯄ꯭ꯔꯣꯁꯦꯁ ꯑꯗꯨ ꯌꯨ.ꯄꯤ.ꯑꯦꯁ., ꯑꯃꯁꯨꯡ ꯏ.ꯄꯤ.

• ꯀꯣꯔꯅꯥꯀꯀꯦꯄꯁ ꯑꯁꯤ ꯖꯤ.ꯑꯦꯝ.ꯄꯤ.ꯒꯤ ꯁ꯭ꯇꯦꯟꯗꯔꯗꯁꯤꯡꯒꯤ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯆꯠꯂꯤ, ꯑꯋꯥꯡꯕꯥ-ꯀ꯭ꯕꯥꯂꯤꯇꯤ ꯑꯃꯁꯨꯡ ꯍꯥꯏ-ꯇꯦꯛ ꯑꯣꯇꯣꯃꯦꯇꯤꯛ ꯀꯦꯄꯁꯨꯜ ꯃꯦꯟꯌꯨꯐꯦꯀꯆꯔꯤꯡ ꯃꯦꯁꯤꯅꯔꯤ ꯁꯤꯖꯤꯟꯅꯩ, ꯑꯦꯛꯁꯦꯂꯦꯟꯁ, ꯄꯔꯐꯦꯛꯇ ꯀ꯭ꯕꯥꯂꯤꯇꯤꯒꯤ ꯄ꯭ꯔꯗꯛꯁꯟ ꯐꯤꯂꯣꯁꯣꯐꯤ ꯉꯥꯛꯅꯥ ꯆꯠꯂꯤ ꯑꯃꯁꯨꯡ ꯀꯣꯔꯅꯥꯛ ꯀꯦꯄꯁꯨꯂꯁꯤꯡꯒꯤ ꯃꯄꯨꯡ ꯐꯥꯕꯥ ꯃꯒꯨꯟ ꯁꯣꯏꯗꯅꯥ ꯐꯪꯍꯟꯅꯕꯥ ꯃꯜꯇꯤ-ꯆꯦꯅꯦꯜ ꯑꯀꯅꯕꯥ ꯀ꯭ꯕꯥꯂꯤꯇꯤ ꯃꯦꯅꯦꯖꯃꯦꯟꯇ ꯉꯥꯛꯅꯥ ꯆꯠꯂꯤ꯫

 

• ꯄ꯭ꯔꯗꯛꯁꯟ ꯃꯦꯅꯦꯖꯃꯦꯟꯇ ꯑꯃꯁꯨꯡ 6S ꯑꯣꯟ-ꯁꯥꯏꯠ ꯃꯦꯅꯦꯖꯃꯦꯟꯇ ꯑꯁꯤ ꯑꯀꯅꯕꯥ ꯃꯑꯣꯡꯗꯥ ꯔꯤꯒꯨꯂꯦꯠ ꯇꯧꯕꯥ, ꯃꯤꯛꯁ ꯕꯦꯆ, ꯕ꯭ꯂꯦꯟꯗꯤꯡ, ꯑꯁꯤꯅꯆꯤꯡꯕꯥ ꯊꯤꯡꯅꯕꯥ ꯏꯐꯦꯛꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯉꯥꯀꯊꯣꯀꯄꯥ ꯑꯃꯥ ꯑꯣꯏꯈꯤ꯫

ꯂꯥꯛꯁꯤꯟꯕ

꯱.ꯔꯣ ꯃꯦꯇꯔꯤꯌꯦꯜ꯫

2. ꯔꯣ ꯃꯦꯇꯔꯤꯌꯦꯜ ꯇꯦꯁ꯭ꯠ ꯇꯧꯕꯥ꯫

꯳.ꯃꯦꯜꯇꯤꯡ ꯇꯧꯕꯥ꯫

ꯀꯦꯄꯁꯨꯜ ꯄꯨꯊꯣꯀꯄꯥ ꯴

꯵.ꯄ꯭ꯔꯤꯟꯇꯤꯡ(ꯔꯤꯛꯕꯦꯁ꯭ꯠ ꯇꯧꯕꯥ)

꯶.ꯃꯦꯁꯤꯅꯅꯥ ꯌꯦꯡꯁꯤꯅꯕꯥ꯫

꯷.ꯀꯥꯎꯟꯇ ꯇꯧꯕꯥ ꯑꯃꯁꯨꯡ ꯄꯦꯀꯤꯡ ꯇꯧꯕꯥ꯫

꯸.ꯂꯦꯕꯇꯥ ꯄꯣꯠꯊꯣꯛ ꯌꯦꯡꯁꯤꯅꯕꯥ꯫

ꯑꯩꯈꯣꯌꯒꯤ ꯄꯣꯠꯊꯣꯀꯁꯤꯡ ꯑꯁꯤ ꯆꯥꯏꯅꯥꯒꯤ ꯐꯥꯔꯃꯥꯀꯣꯄꯤꯌꯥꯒꯤ ꯁ꯭ꯇꯦꯟꯗꯔꯗꯁꯤꯡꯒꯥ ꯃꯥꯟꯅꯩ ꯑꯃꯁꯨꯡ ꯍꯥꯂꯥꯜ, ꯀꯣꯁꯦꯔ, ꯑꯦꯐ.ꯗꯤ.ꯑꯦ., ꯑꯥꯏ.ꯑꯦꯁ.ꯑꯣ.꯹꯰꯰꯱, ꯑꯃꯁꯨꯡ ꯑꯥꯏ.ꯑꯦꯁ.ꯑꯣ.꯲꯲꯰꯰꯰ ꯌꯥꯑꯣꯅꯥ ꯃꯁꯤꯡ ꯌꯥꯝꯂꯕꯥ ꯏꯟꯇꯔꯅꯦꯁ꯭ꯅꯦꯜ ꯁꯔꯇꯤꯐꯤꯀꯦꯁꯅꯁꯤꯡ ꯄꯥꯁ ꯇꯧꯈ꯭ꯔꯦ꯫

ꯄꯦꯀꯦꯖꯤꯡ ꯇꯧꯕꯥ꯫

● ꯄꯤ.ꯏ.ꯕꯦꯒ+ꯑꯦꯂꯨꯃꯤꯅꯤꯌꯝ ꯐꯣꯏꯜ ꯕꯦꯒ+ꯁꯤꯛꯁ ꯁꯔꯐꯦꯁ ​​ꯐꯣꯝ ꯕꯣꯔꯗ+5 ꯄ꯭ꯂꯥꯏ ꯀꯣꯔꯦꯒꯦꯇꯦꯗ ꯀꯥꯔꯇꯟ;

● ꯀꯥꯔꯇꯣꯅꯒꯤ ꯁꯥꯏꯖ ꯶꯰x꯷꯳x꯴꯰ꯁꯦ.ꯃꯤ.,ꯚꯣꯜꯌꯨꯝ ꯰.꯱꯸ ꯀ꯭ꯌꯨꯕꯤꯛ ꯃꯤꯇꯔ,ꯒ꯭ꯔꯣꯁ ꯑꯣꯖꯟ ꯑꯁꯤ ꯕꯣꯛꯁ ꯑꯃꯗꯥ ꯆꯥꯎꯔꯥꯛꯅꯥ ꯀꯤꯂꯣꯒ꯭ꯔꯥꯝ ꯱꯵ꯅꯤ;

● ꯲꯰' ꯔꯦꯐ꯭ꯔꯤꯖꯔꯦꯇꯔ ꯀꯟꯇꯦꯅꯔ : ꯀꯥꯔꯇꯣꯟ ꯱꯴꯰ꯒꯤ ꯑꯍꯥꯡꯕꯥ ꯀꯦꯄꯁꯨꯜ;

● ꯴꯰' ꯔꯦꯐ꯭ꯔꯤꯖꯔꯦꯇꯔ ꯀꯟꯇꯦꯅꯔ: ꯀꯥꯔꯇꯣꯟ ꯳꯴꯵ꯒꯤ ꯑꯍꯥꯡꯕꯥ ꯀꯦꯄꯁꯨꯂꯁꯤꯡ꯫

 

ꯊꯝꯐꯝ

1.ꯑꯍꯥꯡꯕꯥ ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯗꯨ ꯔꯨꯃꯗꯥ ꯇꯦꯝꯄꯦꯔꯦꯆꯔ 10-25 ꯗꯤꯒ꯭ꯔꯤ ꯑꯃꯁꯨꯡ ꯔꯤꯂꯦꯇꯤꯚ ꯍꯨꯃꯤꯗꯤꯇꯤ 35-65%ꯒꯤ ꯃꯔꯛꯇꯥ ꯊꯃꯒꯗꯕꯅꯤ꯫

2.ꯀꯦꯄꯁꯨꯜ ꯀꯥꯔꯇꯟ ꯑꯁꯤ ꯋꯥꯂꯁꯤꯡꯗꯒꯤ ꯂꯥꯞꯅꯥ ꯊꯃꯒꯗꯕꯅꯤ ꯑꯃꯁꯨꯡ ꯐ꯭ꯂꯣꯔꯗꯒꯤ ꯑꯀꯛꯅꯕꯥ ꯂꯥꯞꯅꯥ ꯊꯃꯒꯗꯕꯅꯤ ꯃꯗꯨꯅꯥ ꯃꯩꯁꯥ ꯌꯥꯑꯣꯗꯅꯕꯥ .

3.ꯍꯀꯊꯦꯡꯅꯕꯥ ꯅꯨꯃꯤꯠꯀꯤ ꯃꯉꯥꯜ ꯊꯣꯀꯍꯟꯗꯕꯥ,ꯍꯤꯠ ꯖꯦꯅꯦꯔꯦꯁꯟ ꯑꯃꯁꯨꯡ ꯏꯁꯤꯡꯒꯤ ꯁꯣꯔꯁꯁꯤꯡꯗꯒꯤ ꯂꯥꯞꯅꯥ ꯂꯩꯌꯨ꯫

 

ꯀꯁ꯭ꯇꯃꯔꯒꯤ ꯃꯊꯧ ꯇꯥꯕꯒꯤ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯀꯁ꯭ꯇꯃꯔꯒꯤꯗꯃꯛ ꯐꯪꯒꯅꯤ꯫

ꯍꯥꯏꯗ꯭ꯔꯣꯛꯁꯤꯞꯔꯣꯄꯥꯏꯜ ꯃꯤꯊꯥꯏꯂꯁꯦꯂꯨꯂꯣꯖ (ꯑꯩꯆ.ꯄꯤ.ꯑꯦꯝ.ꯁꯤ.) ꯀꯦꯄꯁꯨꯜ ꯑꯃꯁꯨꯡ ꯖꯦꯂꯇꯤꯟ ꯀꯦꯄꯁꯨꯜ ꯑꯁꯤ ꯐꯥꯔꯃꯥꯁ꯭ꯌꯨꯇꯤꯀꯦꯜ ꯑꯃꯁꯨꯡ ꯅ꯭ꯌꯨꯠꯔꯥꯁ꯭ꯌꯨꯇꯤꯀꯦꯜ ꯏꯟꯗꯁ꯭ꯠꯔꯤꯁꯤꯡꯗꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯌꯥꯝꯅꯥ ꯁꯤꯖꯤꯟꯅꯕꯥ ꯀꯦꯄꯁꯨꯜ ꯃꯈꯜ ꯑꯅꯤꯅꯤ꯫ ꯑꯅꯤꯃꯛꯅꯥ ꯑꯦꯛꯇꯤꯕ ꯏꯅꯒ꯭ꯔꯦꯗꯤꯌꯦꯟꯇꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯏꯐꯦꯛꯇꯤꯕ ꯗꯦꯂꯤꯕꯔꯤ ꯁꯤꯁ꯭ꯇꯦꯝ ꯑꯣꯏꯅꯥ ꯊꯕꯛ ꯇꯧꯔꯕꯁꯨ, ꯃꯈꯣꯌꯒꯤ ꯍꯧꯔꯀꯐꯝ, ꯃꯑꯣꯡ ꯃꯇꯧ, ꯃꯃꯜ, ꯑꯃꯁꯨꯡ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯌꯨꯖꯔ ꯀꯥꯡꯂꯨꯄꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯆꯨꯅꯕꯥ ꯃꯑꯣꯡꯗꯥ ꯌꯥꯝꯅꯥ ꯈꯦꯠꯅꯩ꯫

꯱.ꯀꯝꯄꯣꯖꯤꯁꯟ ꯑꯃꯁꯨꯡ ꯁꯣꯔꯁ꯫
ꯖꯦꯂꯦꯇꯤꯟ ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯃꯍꯧꯁꯥꯅꯥ ꯕꯣꯋꯤꯟ ꯅꯠꯠꯔꯒꯥ ꯄꯣꯔꯁꯤꯟ ꯁꯣꯔꯁꯁꯤꯡꯗꯒꯤ ꯂꯧꯕꯥ ꯑꯦꯅꯤꯃꯦꯜ ꯀꯣꯂꯥꯖꯦꯅꯗꯒꯤ ꯂꯧꯏ꯫ ꯃꯈꯣꯌ ꯑꯁꯤ ꯍꯤꯠ-ꯗꯥ ꯌꯨꯝꯐꯝ ꯑꯣꯏꯕꯥ ꯖꯦꯂꯤꯡ ꯄ꯭ꯔꯣꯁꯦꯁ ꯑꯃꯒꯤ ꯈꯨꯠꯊꯥꯡꯗꯥ ꯁꯦꯝꯕꯅꯤ ꯑꯃꯁꯨꯡ ꯃꯈꯣꯌꯒꯤ ꯃꯁꯛ ꯊꯣꯀꯄꯥ ꯇꯦꯛꯁꯆꯔ ꯑꯃꯁꯨꯡ ꯐ꯭ꯂꯦꯛꯁꯤꯕꯤꯂꯤꯇꯤꯒꯤꯗꯃꯛꯇꯥ ꯈꯪꯅꯩ꯫
ꯃꯁꯤꯒꯥ ꯃꯥꯟꯅꯅꯥ, HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯄ꯭ꯂꯥꯟꯇ-ꯗꯥ ꯌꯨꯝꯐꯝ ꯑꯣꯏ ꯑꯃꯁꯨꯡ ꯄꯥꯏꯟ ꯅꯠꯠꯔꯒꯥ ꯁꯨꯇꯤꯒꯤ ꯐꯤꯕꯃꯗꯒꯤ ꯂꯧꯕꯥ ꯁꯦꯂꯨꯂꯣꯖꯗꯒꯤ ꯁꯦꯝꯕꯅꯤ꯫ ꯃꯈꯣꯌ ꯑꯁꯤ ꯚꯦꯖꯦꯇꯦꯔꯤꯌꯥꯅꯁꯤꯡ, ꯚꯦꯒꯥꯅꯁꯤꯡ, ꯑꯃꯁꯨꯡ ꯗꯥꯏꯑꯦꯇꯔꯤ, ꯙꯔꯝꯃꯒꯤ ꯅꯠꯠꯔꯒꯥ ꯏꯊꯤꯀꯦꯂꯒꯤ ꯃꯔꯃꯁꯤꯡꯅꯥ ꯁꯥ-ꯁꯟ-ꯗꯒꯤ ꯂꯧꯊꯣꯀꯄꯥ ꯄꯣꯠꯊꯣꯀꯁꯤꯡꯗꯒꯤ ꯂꯥꯞꯅꯥ ꯂꯩꯕꯥ ꯃꯤꯑꯣꯏꯁꯤꯡꯒꯤꯗꯃꯛ ꯆꯨꯝꯃꯤ꯫

2. ꯍꯀꯆꯥꯡꯒꯤ ꯃꯑꯣꯡ ꯃꯇꯧꯁꯤꯡ꯫
ꯖꯦꯂꯦꯇꯤꯟ ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯃꯌꯦꯛ ꯁꯦꯡꯏ, ꯃꯌꯦꯛ ꯁꯦꯡꯏ ꯑꯃꯁꯨꯡ ꯑꯐꯕꯥ ꯃꯦꯀꯥꯅꯤꯀꯦꯜ ꯄ꯭ꯔꯣꯄꯔꯇꯤ ꯂꯩ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯃꯈꯣꯌ ꯑꯁꯤ ꯇꯦꯝꯄꯦꯔꯦꯆꯔ ꯑꯃꯁꯨꯡ ꯍꯨꯃꯤꯗꯤꯇꯤꯗꯥ ꯁꯦꯟꯁꯤꯇꯤꯚ ꯑꯣꯏ ꯑꯃꯁꯨꯡ ꯁꯨꯡꯕꯥ ꯀꯟꯗꯤꯁꯅꯁꯤꯡꯗꯥ ꯕ꯭ꯔꯤꯇꯤꯜ ꯑꯣꯏꯕꯥ ꯌꯥꯏ ꯅꯠꯠꯔꯒꯥ ꯑꯋꯥꯡꯕꯥ ꯍꯨꯃꯤꯗꯤꯇꯤꯗꯥ ꯂꯦꯡ-ꯑꯣꯠꯄꯥ ꯌꯥꯏ꯫
HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯍꯦꯟꯅꯥ ꯄꯥꯛ-ꯆꯥꯎꯕꯥ ꯁ꯭ꯇꯣꯔꯦꯖ ꯀꯟꯗꯤꯁꯅꯁꯤꯡꯒꯤ ꯃꯈꯥꯗꯥ ꯍꯦꯟꯅꯥ ꯁ꯭ꯇꯦꯕꯜ ꯑꯣꯏ꯫ ꯃꯈꯣꯌ ꯑꯁꯤ ꯐꯖꯅꯥ ꯁꯣꯟꯊꯕꯥ ꯉꯃꯗꯦ ꯑꯃꯁꯨꯡ ꯃꯈꯣꯌꯒꯤ ꯃꯑꯣꯡ-ꯃꯇꯧ ꯑꯗꯨ ꯂꯦꯡ-ꯑꯣꯠꯄꯒꯤ ꯆꯥꯡ ꯅꯦꯝꯕꯥ ꯑꯀꯣꯌꯔꯣꯅꯁꯤꯡꯗꯁꯨ ꯊꯃꯖꯤꯜꯂꯤ꯫ HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯍꯥꯏꯒ꯭ꯔꯣꯁ꯭ꯀꯣꯄꯤꯛ ꯏꯅꯒ꯭ꯔꯦꯗꯤꯌꯦꯟꯇꯁꯤꯡꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯅꯟ-ꯔꯤꯑꯦꯛꯇꯤꯕ ꯑꯣꯏꯕꯁꯨ ꯌꯥꯏ, ꯃꯁꯤꯅꯥ ꯃꯈꯣꯌꯕꯨ ꯃꯩꯁꯥ-ꯁꯦꯟꯁꯤꯇꯤꯕ ꯐꯣꯔꯃꯨꯂꯦꯁꯅꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯌꯥꯝꯅꯥ ꯐꯕꯥ ꯑꯣꯏꯍꯜꯂꯤ꯫

꯳.ꯗꯤꯁꯜꯌꯨꯁꯟ ꯑꯃꯁꯨꯡ ꯕꯥꯏꯑꯣꯑꯦꯕꯦꯂꯤꯕꯤꯂꯤꯇꯤ꯫
ꯀꯦꯄꯁꯨꯜ ꯃꯈꯜ ꯑꯅꯤꯃꯛ ꯑꯁꯤ ꯈꯣꯡꯗꯥ ꯏꯐꯤꯁꯤꯑꯦꯟꯇ ꯑꯣꯏꯅꯥ ꯁꯣꯀꯏ, ꯑꯗꯨꯕꯨ HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯃꯈꯣꯌꯒꯤ ꯁ꯭ꯠꯔꯀꯆꯔꯅꯥ ꯃꯔꯝ ꯑꯣꯏꯗꯨꯅꯥ ꯖꯦꯂꯇꯤꯟ ꯀꯦꯄꯁꯨꯂꯁꯤꯡꯗꯒꯤ ꯈꯔꯥ ꯍꯦꯟꯅꯥ ꯇꯞꯅꯥ ꯁꯣꯀꯄꯥ ꯌꯥꯏ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯈꯦꯠꯅꯕꯥ ꯑꯁꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯅꯦꯝꯃꯤ ꯑꯃꯁꯨꯡ ꯑꯌꯥꯝꯕꯥ ꯑꯦꯞꯂꯤꯀꯦꯁꯅꯁꯤꯡꯗꯥ ꯑꯄꯨꯅꯕꯥ ꯕꯥꯏꯑꯣꯑꯦꯕꯦꯂꯤꯕꯤꯂꯤꯇꯤꯗꯥ ꯑꯀꯥꯌꯕꯥ ꯄꯤꯕꯥ ꯌꯥꯝꯅꯥ ꯊꯦꯡꯅꯗꯦ꯫ HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯊꯦꯡꯊꯕꯥ ꯅꯠꯠꯔꯒꯥ ꯀꯟꯠꯔꯣꯜ ꯇꯧꯔꯕꯥ ꯔꯤꯂꯤꯖꯒꯤꯗꯃꯛꯇꯁꯨ ꯃꯣꯗꯤꯐꯥꯏ ꯇꯧꯕꯥ ꯌꯥꯏ, ꯃꯁꯤꯅꯥ ꯗ꯭ꯔꯒ ꯄꯤꯕꯗꯥ ꯍꯦꯟꯅꯥ ꯐ꯭ꯂꯦꯛꯁꯤꯕꯤꯂꯤꯇꯤ ꯄꯤꯔꯤ꯫

ꯃꯃꯜ ꯆꯥꯡꯗꯝꯅꯕꯥ ꯴
ꯃꯍꯧꯁꯥꯅꯥ, ꯖꯦꯂꯇꯤꯟ ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯂꯤꯡꯈꯠꯂꯛꯂꯤꯕꯥ ꯁꯞꯂꯥꯏ ꯆꯦꯟ ꯑꯃꯁꯨꯡ ꯃꯦꯟꯌꯨꯐꯦꯀꯆꯔꯤꯡꯒꯤ ꯃꯃꯜ ꯍꯟꯊꯕꯅꯥ ꯃꯔꯝ ꯑꯣꯏꯗꯨꯅꯥ ꯍꯦꯟꯅꯥ ꯃꯃꯜ-ꯏꯐꯦꯛꯇꯤꯕ ꯑꯣꯏ꯫ HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯃꯈꯣꯌꯒꯤ ꯄ꯭ꯂꯥꯟꯇ-ꯗꯥ ꯌꯨꯝꯐꯝ ꯑꯣꯏꯕꯥ ꯁꯣꯔꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯀꯝꯞꯂꯦꯛꯁ ꯄ꯭ꯔꯗꯛꯁꯟ ꯄ꯭ꯔꯣꯁꯦꯁꯅꯥ ꯃꯔꯝ ꯑꯣꯏꯗꯨꯅꯥ ꯃꯃꯜ ꯌꯥꯝꯅꯥ ꯆꯪꯏ-ꯃꯍꯧꯁꯥꯅꯥ ꯃꯃꯜ 20–40% ꯍꯦꯟꯅꯥ ꯋꯥꯡꯏ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯍꯀꯁꯦꯂꯒꯤ-ꯀꯟꯁꯤꯌꯦꯟꯇ ꯅꯠꯠꯔꯒꯥ ꯚꯦꯖꯦꯇꯦꯔꯤꯌꯟ ꯃꯥꯔꯀꯦꯠꯇꯥ ꯄꯥꯟꯗꯝ ꯊꯝꯂꯤꯕꯥ ꯕ꯭ꯔꯥꯟꯗꯁꯤꯡꯒꯤ ꯑꯣꯏꯅꯗꯤ, ꯑꯍꯦꯅꯕꯥ ꯃꯃꯜ ꯑꯁꯤ ꯑꯌꯥꯝꯕꯅꯥ ꯆꯨꯝꯃꯤ꯫

ꯑꯦꯞꯂꯤꯀꯦꯁꯅꯁꯤꯡ ꯵
ꯖꯦꯂꯦꯇꯤꯟ ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯐꯥꯔꯃꯥꯁ꯭ꯌꯨꯇꯤꯀꯦꯂꯁꯤꯡ, ꯗꯥꯏꯑꯦꯇꯦꯔꯤ ꯁꯞꯂꯤꯃꯦꯟꯇꯁꯤꯡ, ꯑꯃꯁꯨꯡ ꯑꯣꯚꯔ-ꯀꯥꯎꯟꯇꯔ ꯃꯦꯗꯤꯀꯦꯁꯅꯁꯤꯡꯗꯥ ꯄꯥꯛ ꯁꯟꯅꯥ ​​ꯁꯤꯖꯤꯟꯅꯩ꯫ ꯃꯈꯣꯌ ꯑꯁꯤ ꯃꯔꯨꯑꯣꯏꯅꯥ ꯅꯟ--ꯁꯦꯟꯁꯤꯇꯤꯚ ꯏꯅꯒ꯭ꯔꯦꯗꯤꯌꯦꯟꯇꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯌꯥꯡꯅꯥ ꯔꯤꯂꯤꯖ ꯇꯧꯕꯥ ꯃꯊꯧ ꯇꯥꯕꯥ ꯄꯣꯠꯊꯣꯀꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯆꯨꯝꯃꯤ꯫
HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯃꯍꯧꯁꯥꯒꯤ ꯍꯀꯁꯦꯜ, ꯚꯦꯒꯥꯟ, ꯑꯃꯁꯨꯡ ꯑꯣꯔꯒꯥꯅꯤꯛ ꯁꯦꯛꯇꯔꯁꯤꯡꯗꯥ ꯍꯦꯟꯅꯥ ꯄꯥꯝꯃꯤ꯫ ꯃꯈꯣꯌ ꯑꯁꯤ ꯃꯩꯁꯥ-ꯁꯦꯟꯁꯤꯇꯤꯚ, pH-ꯁꯦꯟꯁꯤꯇꯤꯚ, ꯅꯠꯠꯔꯒꯥ ꯇꯦꯝꯄꯦꯔꯦꯆꯔ-ꯁꯦꯟꯁꯤꯇꯤꯚ ꯑꯣꯏꯕꯥ ꯄꯣꯠꯁꯀꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯌꯥꯝꯅꯥ ꯐꯩ꯫ ꯃꯈꯣꯌ ꯑꯁꯤ ꯀꯣꯁꯦꯔ ꯑꯃꯁꯨꯡ ꯍꯂꯥꯜ ꯁꯔꯇꯤꯐꯥꯏꯗ ꯇꯧꯕꯁꯨ ꯌꯥꯏ, ꯃꯁꯤꯅꯥ ꯃꯥꯂꯦꯃꯒꯤ ꯀꯟꯖꯨꯃꯔꯁꯤꯡꯒꯤ ꯄꯥꯛ ꯆꯥꯎꯔꯕꯥ ꯔꯦꯟꯖ ꯑꯃꯗꯥ ꯌꯥꯕꯥ ꯉꯃꯍꯜꯂꯤ꯫

꯶.ꯃꯊꯧ ꯇꯥꯕꯥ ꯌꯨꯖꯔ ꯒ꯭ꯔꯨꯄꯁꯤꯡ꯫

ꯖꯦꯂꯦꯇꯤꯟ ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯁꯥ-ꯁꯅꯒꯤ ꯄꯣꯠꯊꯣꯀꯁꯤꯡꯒꯥ ꯃꯔꯤ ꯂꯩꯅꯕꯥ ꯗꯥꯏꯑꯦꯇꯔꯤꯒꯤ ꯑꯊꯤꯡꯕꯥ ꯂꯩꯇꯕꯥ ꯖꯦꯅꯦꯔꯦꯜ ꯄꯣꯄꯨꯂꯦꯁꯅꯒꯤꯗꯃꯛꯇꯥ ꯆꯨꯝꯃꯤ꯫

HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯚꯦꯖꯦꯇꯦꯔꯤꯌꯅꯁꯤꯡ, ꯚꯦꯒꯥꯅꯁꯤꯡ, ꯙꯔꯃꯒꯤ ꯑꯣꯏꯕꯥ ꯗꯥꯏꯑꯦꯇꯔꯤꯒꯤ ꯑꯥꯏꯟ ꯂꯩꯕꯥ ꯃꯤꯑꯣꯏꯁꯤꯡ (ꯀꯣꯁꯦꯔ, ꯍꯂꯥꯜ), ꯑꯃꯁꯨꯡ ꯁꯥ-ꯁꯅꯁꯤꯡꯒꯥ ꯃꯔꯤ ꯂꯩꯅꯕꯥ ꯈꯨꯗꯣꯡꯊꯤꯕꯁꯤꯡꯒꯨꯝꯕꯥ ꯖꯦꯂꯇꯤꯅꯒꯤ ꯁꯦꯐꯇꯤꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯋꯥꯈꯜ ꯋꯥꯕꯥ ꯃꯤꯑꯣꯏꯁꯤꯡꯒꯤꯗꯃꯛ ꯆꯨꯝꯃꯤ꯫

ꯂꯣꯏꯁꯤꯟꯕ
ꯑꯩꯆ.ꯄꯤ.ꯑꯦꯝ.ꯁꯤ. ꯑꯃꯁꯨꯡ ꯖꯦꯂꯇꯤꯟ ꯀꯦꯄꯁꯨꯜ ꯑꯅꯤꯃꯛꯀꯤ ꯃꯁꯥꯒꯤ ꯑꯣꯏꯕꯥ ꯄꯥꯉ꯭ꯒꯜ ꯂꯩ꯫ ꯈꯅꯕꯁꯤ ꯄꯣꯠꯊꯣꯛ ꯐꯣꯔꯃꯨꯂꯦꯁꯟ, ꯇꯥꯔꯒꯦꯠ ꯀꯟꯖꯨꯃꯔ ꯒ꯭ꯔꯨꯞ, ꯑꯃꯁꯨꯡ ꯕ꯭ꯔꯥꯟꯗ ꯄꯣꯖꯤꯁꯅꯒꯤ ꯃꯈꯥ ꯄꯣꯜꯂꯤ꯫ ꯄ꯭ꯂꯥꯟꯇ-ꯕꯦꯖ, ꯏꯊꯤꯀꯦꯜ, ꯑꯃꯁꯨꯡ ꯑꯦꯂꯔꯖꯦꯟ-ꯐ꯭ꯔꯤ ꯁꯞꯂꯤꯃꯦꯟꯇꯁꯤꯡꯒꯤ ꯗꯤꯃꯥꯟꯗ ꯑꯁꯤ ꯃꯈꯥ ꯇꯥꯅꯥ ꯍꯦꯅꯒꯠꯂꯀꯄꯒꯥ ꯂꯣꯌꯅꯅꯥ, HPMC ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯃꯈꯣꯌꯒꯤ ꯃꯃꯜ ꯍꯦꯟꯅꯥ ꯋꯥꯡꯂꯕꯁꯨ ꯍꯦꯟꯅꯥ ꯄꯥꯝꯅꯕꯥ ꯑꯣꯄꯁꯟ ꯑꯣꯏꯔꯛꯂꯤ꯫

ꯍꯠ ꯇꯦꯒꯁ: ꯁꯥꯏꯖ ꯲ hpmc ꯀꯦꯄꯁꯨꯜ, ꯆꯥꯏꯅꯥ ꯁꯥꯏꯖ ꯲ hpmc ꯀꯦꯄꯁꯨꯜ ꯃꯦꯟꯌꯨꯐꯦꯀꯆꯔꯔꯁꯤꯡ, ꯁꯞꯂꯥꯏꯌꯔꯁꯤꯡ, ꯐꯦꯛꯇꯔꯤ꯫